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WNT7a induces E-cadherin in lung cancer cells

E-cadherin loss in cancer is associated with de-differentiation, invasion, and metastasis. Drosophila DE-cadherin is regulated by Wnt/β-catenin signaling, although this has not been demonstrated in mammalian cells. We previously reported that expression of WNT7a, encoded on 3p25, was frequently down...

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Uloženo v:
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Ohira, Tatsuo, Gemmill, Robert M., Ferguson, Kevin, Kusy, Sophie, Roche, Joëlle, Brambilla, Elisabeth, Zeng, Chan, Baron, Anna, Bemis, Lynne, Erickson, Paul, Wilder, Elizabeth, Rustgi, Anil, Kitajewski, Jan, Gabrielson, Edward, Bremnes, Roy, Franklin, Wilbur, Drabkin, Harry A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC193578/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12937339/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1734137100
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