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Expression deconvolution: A reinterpretation of DNA microarray data reveals dynamic changes in cell populations

Cells grow in dynamically evolving populations, yet this aspect of experiments often goes unmeasured. A method is proposed for measuring the population dynamics of cells on the basis of their mRNA expression patterns. The population's expression pattern is modeled as the linear combination of mRNA e...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Lu, Peng, Nakorchevskiy, Aleksey, Marcotte, Edward M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC193568/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12934019/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1832361100
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