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A small engineered protein lacks structural uniqueness by increasing the side-chain conformational entropy

A small globular protein, the third repeat of the c-Myb DNA-binding domain, which is composed of 54 amino acid residues, was engineered so as to understand the structural uniqueness of native proteins. This small protein has three α-helices that form a helix-turn-helix structure, which is maintained...

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Autori principali: Furukawa, Koji, Oda, Masayuki, Nakamura, Haruki
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC19356/
https://ncbi.nlm.nih.gov/pubmed/8942977
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