Nuclear receptor ERRα and coactivator PGC-1β are effectors of IFN-γ-induced host defense

Macrophage activation by the proinflammatory cytokine interferon-γ (IFN-γ) is a critical component of the host innate response to bacterial pathogenesis. However, the precise nature of the IFN-γ-induced activation pathway is not known. Here we show using genome-wide expression and chromatin-binding...

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Detalhes bibliográficos
Main Authors: Sonoda, Junichiro, Laganière, Josée, Mehl, Isaac R., Barish, Grant D., Chong, Ling-Wa, Li, Xiangli, Scheffler, Immo E., Mock, Dennis C., Bataille, Alain R., Robert, François, Lee, Chih-Hao, Giguère, Vincent, Evans, Ronald M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1935029/
https://ncbi.nlm.nih.gov/pubmed/17671090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1553007
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