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p21 transcription is regulated by differential localization of histone H2A.Z

In yeast cells, H2A.Z regulates transcription and is globally associated within a few nucleosomes of the initiator regions of numerous promoters. H2A.Z is deposited at these loci by an ATP-dependent complex, Swr1.com. Here we show that H2A.Z suppresses the p53 → p21 transcription and senescence resp...

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Detalles Bibliográficos
Main Authors: Gévry, Nicolas, Chan, Ho Man, Laflamme, Liette, Livingston, David M., Gaudreau, Luc
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1935026/
https://ncbi.nlm.nih.gov/pubmed/17671089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1545707
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