Aberrant allele frequencies of the SNPs located in microRNA target sites are potentially associated with human cancers

MicroRNAs (miRNAs) are a class of noncoding small RNAs that regulate gene expression by base pairing with target mRNAs at the 3′-terminal untranslated regions (3′-UTRs), leading to mRNA cleavage or translational repression. Single-nucleotide polymorphisms (SNPs) located at miRNA-binding sites (miRNA...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Yu, Zhenbao, Li, Zhen, Jolicoeur, Normand, Zhang, Linhua, Fortin, Yves, Wang, Edwin, Wu, Meiqun, Shen, Shi-Hsiang
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2007
Sujets:
Genomics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1935019/
https://ncbi.nlm.nih.gov/pubmed/17584784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm480
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