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RNA structure is a key regulatory element in pathological ATM and CFTR pseudoexon inclusion events

Genomic variations deep in the intronic regions of pre-mRNA molecules are increasingly reported to affect splicing events. However, there is no general explanation why apparently similar variations may have either no effect on splicing or cause significant splicing alterations. In this work we have...

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Detalhes bibliográficos
Main Authors: Buratti, Emanuele, Dhir, Ashish, Lewandowska, Marzena A., Baralle, Francisco E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1935003/
https://ncbi.nlm.nih.gov/pubmed/17580311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm447
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