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Efficient splicing correction by PNA conjugation to an R(6)-Penetratin delivery peptide
Sequence-specific interference with the nuclear pre-mRNA splicing machinery has received increased attention as an analytical tool and for development of therapeutics. It requires sequence-specific and high affinity binding of RNaseH-incompetent DNA mimics to pre-mRNA. Peptide nucleic acids (PNA) or...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1934994/ https://ncbi.nlm.nih.gov/pubmed/17584792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm418 |
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