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Induction of Apoptosis by Tumor Suppressor FHIT via Death Receptor Signaling Pathway in Human Lung Cancer Cells
FHIT is a novel tumor suppressor gene located at human chromosome 3p14.2. Restoration of wild-type FHIT in 3p14.2-deficient human lung cancer cells inhibits cell growth and induces apoptosis. In this study, we analyzed potential upstream/downstream molecular targets of the FHIT protein and found tha...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1934611/ https://ncbi.nlm.nih.gov/pubmed/17328863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.02.067 |
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