Mice Deficient for the Type II Transmembrane Serine Protease, TMPRSS1/hepsin, Exhibit Profound Hearing Loss

Defective proteolysis has been implicated in hearing loss through the discovery of mutations causing autosomal recessive nonsyndromic deafness in a type II transmembrane serine protease gene, TMPRSS3. To investigate their physiological function and the contribution of this family of proteases to the...

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Bibliografiske detaljer
Main Authors: Guipponi, Michel, Tan, Justin, Cannon, Ping Z.F., Donley, Lauren, Crewther, Pauline, Clarke, Maria, Wu, Qingyu, Shepherd, Robert K., Scott, Hamish S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2007
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934525/
https://ncbi.nlm.nih.gov/pubmed/17620368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070068
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