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Cytidine 5′-Diphosphocholine (CDP-Choline) in Stroke and Other CNS Disorders
Brain phosphatidylcholine (PC) levels are regulated by a balance between synthesis and hydrolysis. Pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1 (IL-1α/β) activate phospholipase A(2) (PLA(2)) and PC-phospholipase C (PC-PLC) to hydrolyze PC. PC hydrolysis by PLA...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1934404/ https://ncbi.nlm.nih.gov/pubmed/15756928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-004-9681-8 |
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