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Divergent Evolution of Human p53 Binding Sites: Cell Cycle Versus Apoptosis
The p53 tumor suppressor is a sequence-specific pleiotropic transcription factor that coordinates cellular responses to DNA damage and stress, initiating cell-cycle arrest or triggering apoptosis. Although the human p53 binding site sequence (or response element [RE]) is well characterized, some gen...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1934401/ https://ncbi.nlm.nih.gov/pubmed/17677004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030127 |
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