Thermolabilizing Pseudoreversions in Reovirus Outer-Capsid Protein μ1 Rescue the Entry Defect Conferred by a Thermostabilizing Mutation

Heat-resistant mutants selected from infectious subvirion particles of mammalian reoviruses have determinative mutations in the major outer-capsid protein μ1. Here we report the isolation and characterization of intragenic pseudoreversions of one such thermostabilizing mutation. From a plaque that h...

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Bibliografiska uppgifter
Huvudupphovsmän: Agosto, Melina A., Middleton, Jason K., Freimont, Elaine C., Yin, John, Nibert, Max L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2007
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933377/
https://ncbi.nlm.nih.gov/pubmed/17507494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02720-06
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