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Microtubule-Mediated and Microtubule-Independent Transport of Adenovirus Type 5 in HEK293 Cells

Adenovirus serotypes 2 and 5 are taken into cells by receptor-mediated endocytosis, and following release from endosomes, destabilized virions travel along microtubules to accumulate around the nucleus. The entry process culminates in delivery of the viral genome through nuclear pores. This model is...

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Bibliographic Details
Main Authors: Yea, Carmen, Dembowy, Joanna, Pacione, Laura, Brown, Martha
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933318/
https://ncbi.nlm.nih.gov/pubmed/17442712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02330-05
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