Differential regulation by estrogens of growth and prolactin synthesis in pituitary cells suggests that only a small pool of estrogen receptors is required for growth

PR1 cells are a prolactin (PRL)-secreting cell line derived from a pituitary lactotroph tumor found in 17β-estradiol-treated Fischer 344 rats. We examined the effect of estrogen on cell proliferation and PRL synthesis under various culture conditions. Estrogen, at extremely low concentrations, induc...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Chun, Tae-Yon, Gregg, David, Sarkar, Dipak K., Gorski, Jack
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1998
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19333/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9482884/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.5.2325
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