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A Novel Bcl-2-Like Inhibitor of Apoptosis Is Encoded by the Parapoxvirus Orf Virus

Apoptotic cell death forms part of the host defense against virus infection. We tested orf virus, a member of the poxvirus family, for the ability to inhibit apoptosis and found that orf virus-infected cells were fully resistant to UV-induced changes in cell morphology, caspase activation, and DNA f...

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Bibliografiske detaljer
Main Authors: Westphal, Dana, Ledgerwood, Elizabeth C., Hibma, Merilyn H., Fleming, Stephen B., Whelan, Ellena M., Mercer, Andrew A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933275/
https://ncbi.nlm.nih.gov/pubmed/17475653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00404-07
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