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Both Human Immunodeficiency Virus Cellular DNA Sequencing and Plasma RNA Sequencing Are Useful for Detection of Drug Resistance Mutations in Blood Samples from Antiretroviral-Drug-Naive Patients

Genotypic antiretroviral testing is recommended for newly infected drug-naive subjects, and the material of choice is plasma RNA. Since drug resistance mutations (DRMs) may persist longer in cellular DNA than in plasma RNA, we investigated whether the use of peripheral blood mononuclear cell (PBMC)...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Parisi, Saverio G., Boldrin, Caterina, Cruciani, Mario, Nicolini, Giangiacomo, Cerbaro, Isabella, Manfrin, Vinicio, Dal Bello, Federico, Franchin, Elisa, Franzetti, Marzia, Rossi, Maria C., Cattelan, Anna M., Romano, Laura, Zazzi, Maurizio, Andreoni, Massimo, Palù, Giorgio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933075/
https://ncbi.nlm.nih.gov/pubmed/17442799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00056-07
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