Marginal Zone B-Cell Depletion Impairs Murine Host Defense against Borrelia burgdorferi Infection

Marginal zone B (MZB) cells are a B-cell subset that produces T-cell-independent antibodies to blood-borne antigens. In this study, we examined the effects of MZB cell depletion on the immune response to the Lyme disease spirochete Borrelia burgdorferi, an extracellular pathogen for which T-cell-ind...

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Bibliographic Details
Main Authors: Belperron, Alexia A., Dailey, Catherine M., Booth, Carmen J., Bockenstedt, Linda K.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932939/
https://ncbi.nlm.nih.gov/pubmed/17470546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00422-07
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