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In the Absence of CD154, Administration of Interleukin-12 Restores Th1 Responses but Not Protective Immunity to Schistosoma mansoni

The cytokine interplay during the development of protective immunity to the radiation-attenuated (RA) schistosome vaccine has been extensively characterized over recent years, yet the role of costimulatory molecules in the development of cell-mediated immunity is much less well understood. Here we d...

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Detalhes bibliográficos
Main Authors: Hewitson, James P., Hamblin, Paul A., Mountford, Adrian P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932915/
https://ncbi.nlm.nih.gov/pubmed/17485453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00252-07
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