Nasal Immunization with Burkholderia multivorans Outer Membrane Proteins and the Mucosal Adjuvant Adamantylamide Dipeptide Confers Efficient Protection against Experimental Lung Infections with B. multivorans and B. cenocepacia

Chronic lung infection by opportunistic pathogens, such as Pseudomonas aeruginosa and members of the Burkholderia cepacia complex, is a major cause of morbidity and mortality in patients with cystic fibrosis. Outer membrane proteins (OMPs) of gram-negative bacteria are promising vaccine antigen cand...

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Библиографические подробности
Главные авторы: Bertot, Gustavo M., Restelli, Marcela A., Galanternik, Laura, Aranibar Urey, Rene C., Valvano, Miguel A., Grinstein, Saúl
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2007
Предметы:
Microbial Immunity and Vaccines
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932907/
https://ncbi.nlm.nih.gov/pubmed/17296759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01668-06
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