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Nasal Immunization with Burkholderia multivorans Outer Membrane Proteins and the Mucosal Adjuvant Adamantylamide Dipeptide Confers Efficient Protection against Experimental Lung Infections with B. multivorans and B. cenocepacia

Chronic lung infection by opportunistic pathogens, such as Pseudomonas aeruginosa and members of the Burkholderia cepacia complex, is a major cause of morbidity and mortality in patients with cystic fibrosis. Outer membrane proteins (OMPs) of gram-negative bacteria are promising vaccine antigen cand...

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Detalhes bibliográficos
Main Authors: Bertot, Gustavo M., Restelli, Marcela A., Galanternik, Laura, Aranibar Urey, Rene C., Valvano, Miguel A., Grinstein, Saúl
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932907/
https://ncbi.nlm.nih.gov/pubmed/17296759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01668-06
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