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Alterations in NF-κB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-κB

Stratified epithelium contains a mitotically active basal layer of cells that cease proliferating, then migrate outwards and undergo terminal differentiation. The control of this process, which is abnormal in cutaneous neoplasia and inflammation, is not well understood. In normal epidermis, NF-κB pr...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Seitz, Cornelia S., Lin, Qun, Deng, Helen, Khavari, Paul A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19329/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9482881/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.5.2307
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