Engineering of the Yeast Yarrowia lipolytica for the Production of Glycoproteins Lacking the Outer-Chain Mannose Residues of N-Glycans

In an attempt to engineer a Yarrowia lipolytica strain to produce glycoproteins lacking the outer-chain mannose residues of N-linked oligosaccharides, we investigated the functions of the OCH1 gene encoding a putative α-1,6-mannosyltransferase in Y. lipolytica. The complementation of the Saccharomyc...

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Bibliographische Detailangaben
Hauptverfasser: Song, Yunkyoung, Choi, Min Hee, Park, Jeong-Nam, Kim, Moo Woong, Kim, Eun Jung, Kang, Hyun Ah, Kim, Jeong-Yoon
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Physiology and Biotechnology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932813/
https://ncbi.nlm.nih.gov/pubmed/17513593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02058-06
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