Enhancement of intracellular γ-tocopherol levels in cytokine-stimulated C3H 10T1/2 fibroblasts: relation to NO synthesis, isoprostane formation, and tocopherol oxidation

BACKGROUND: Stimulation of C3H 10T1/2 murine fibroblasts with interferon-γ(IFN) and bacterial lipopolysaccharide (LPS) generates reactive oxygen and nitrogen species leading to DNA damage, lipid oxidation, and tocopherol oxidation. The tocopherols possess unique chemical and biological properties th...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Tanaka, Yuichiro, Wood, Leslie A Lesoon, Cooney, Robert V
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2007
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1931582/
https://ncbi.nlm.nih.gov/pubmed/17608946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6769-7-2
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