Correcting for Measurement Error in Individual Ancestry Estimates in Structured Association Tests

We present theoretical explanations and show through simulation that the individual admixture proportion estimates obtained by using ancestry informative markers should be seen as an error-contaminated measurement of the underlying individual ancestry proportion. These estimates can be used in struc...

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Dettagli Bibliografici
Autori principali: Divers, Jasmin, Vaughan, Laura K., Padilla, Miguel A., Fernandez, José R., Allison, David B., Redden, David T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright © 2007 by the Genetics Society of America 2007
Soggetti:
Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1931538/
https://ncbi.nlm.nih.gov/pubmed/17507670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.075408
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