The Kinetochore Proteins Pcs1 and Mde4 and Heterochromatin Are Required to Prevent Merotelic Orientation

BACKGROUND: Accurate chromosome segregation depends on the establishment of correct—amphitelic—kinetochore orientation. Merotelic kinetochore orientation is an error that occurs when a single kinetochore attaches to microtubules emanating from opposite spindle poles, a condition that hinders segrega...

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Main Authors: Gregan, Juraj, Riedel, Christian G., Pidoux, Alison L., Katou, Yuki, Rumpf, Cornelia, Schleiffer, Alexander, Kearsey, Stephen E., Shirahige, Katsuhiko, Allshire, Robin C., Nasmyth, Kim
Format: Artigo
Language:Inglês
Published: Cell Press 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1931489/
https://ncbi.nlm.nih.gov/pubmed/17627824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2007.06.044
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