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(13)C Enrichment of Carbons 2 and 8 of Purine by Folate-Dependent Reactions After [(13)C]Formate and [2-(13)C]Glycine Dosing in Adult Humans
The 10-formyl moiety of 10-formyltetrahydrofolate is the source of carbons at the positions 8 (C(8)) and 2 (C(2)) of the purine ring, originating from formate and a few amino acids. Uric acid is the final catabolic product of purines. In adult humans, we independently measured the (13)C enrichment o...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1931417/ https://ncbi.nlm.nih.gov/pubmed/17445548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2006.12.020 |
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