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Cyclic AMP and its receptor protein negatively regulate the coordinate expression of cholera toxin and toxin-coregulated pilus in Vibrio cholerae

Insertion mutations in two Vibrio cholerae genes, cya and crp, which encode adenylate cyclase and the cyclic AMP (cAMP) receptor protein (CRP), respectively, derepressed the expression of a chromosomal cholera toxin (CT) promoter–lacZ fusion at the nonpermissive temperature of 37°C. In the classical...

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Detalhes bibliográficos
Main Authors: Skorupski, Karen, Taylor, Ronald K.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC19310/
https://ncbi.nlm.nih.gov/pubmed/8990197
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