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Exacerbation of Retinal Degeneration and Choroidal Neovascularization Induced by Subretinal Injection of Matrigel in CCL2/MCP-1-Deficient Mice

This study presents a mouse model for human age-related macular degeneration (AMD) as characterized by subretinal deposit and choroidal neovascularization. Matrigel, a basement membrane extract, solidifies after implantation in tissue and can stimulate local angiogenesis. This study demonstrates the...

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Detalhes bibliográficos
Main Authors: Shen, Defen, Wen, Rong, Tuo, Jingsheng, Bojanowski, Christine M., Chan, Chi-Chao
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1930147/
https://ncbi.nlm.nih.gov/pubmed/16352919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000090266
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