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Daidzin and its antidipsotropic analogs inhibit serotonin and dopamine metabolism in isolated mitochondria

Daidzin, a major active principle of an ancient Chinese herbal treatment (Radix puerariae) for alcohol abuse, selectively suppresses ethanol intake in all rodent models tested. It also inhibits mitochondrial aldehyde dehydrogenase (ALDH-2). Studies on ethanol intake suppression and ALDH-2 inhibition...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Keung, Wing Ming, Vallee, Bert L.
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 1998
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19293/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9482862/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.5.2198
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