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A dynamic model for PC4 coactivator function in RNA polymerase II transcription

Human positive cofactor (PC4) acts as a general coactivator for activator-dependent transcription by RNA polymerase II. Here we show that PC4 coactivator function, in contrast to basal (activator-independent) transcription, is dependent both on TATA binding protein (TBP)-associated factors (TAFs) in...

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Bibliographic Details
Main Authors: Malik, Sohail, Guermah, Mohamed, Roeder, Robert G.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC19292/
https://ncbi.nlm.nih.gov/pubmed/9482861
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