Association of TP53 codon 72 polymorphism and the outcome of adjuvant therapy in breast cancer patients

INTRODUCTION: Single-nucleotide polymorphisms (SNPs) in codon 72 of the TP53 (also known as p53) gene (rs1042522) and in the promoter region of the MDM2 gene (SNP309; rs2279744) have been suggested to play roles in many cancers. We investigated whether these SNPs were associated with patient outcome...

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Autors principals: Toyama, Tatsuya, Zhang, Zhenhuan, Nishio, Mariko, Hamaguchi, Maho, Kondo, Naoto, Iwase, Hirotaka, Iwata, Hiroji, Takahashi, Satoru, Yamashita, Hiroko, Fujii, Yoshitaka
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1929098/
https://ncbi.nlm.nih.gov/pubmed/17537232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1682
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