Expression profiling of Dexamethasone-treated primary chondrocytes identifies targets of glucocorticoid signalling in endochondral bone development

BACKGROUND: Glucocorticoids (GCs) are widely used anti-inflammatory drugs. While useful in clinical practice, patients taking GCs often suffer from skeletal side effects including growth retardation in children and adolescents, and decreased bone quality in adults. On a physiological level, GCs have...

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Autors principals: James, Claudine G, Ulici, Veronica, Tuckermann, Jan, Underhill, T Michael, Beier, Frank
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1929075/
https://ncbi.nlm.nih.gov/pubmed/17603917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-205
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