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Is Lipid Bilayer Binding a Common Property of Inhibitor Cysteine Knot Ion-Channel Blockers?

Recent studies of several ICK ion-channel blockers suggest that lipid bilayer interactions play a prominent role in their actions. Structural similarities led to the hypothesis that bilayer interactions are important for the entire ICK family. We have tested this hypothesis by performing direct meas...

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Detalhes bibliográficos
Main Authors: Posokhov, Yevgen O., Gottlieb, Philip A., Morales, Michael J., Sachs, Frederick, Ladokhin, Alexey S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1929044/
https://ncbi.nlm.nih.gov/pubmed/17573432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.112375
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