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Kinetic Refolding Barrier of Guanidinium Chloride Denatured Goose δ-Crystallin Leads to Regular Aggregate Formation

δ-Crystallin is the major soluble protein in avian eye lenses with a structural role in light scattering. Dissociation and unfolding of the tetrameric protein in guanidinium chloride (GdmCl) can be sensitively monitored by the intrinsic tryptophan fluorescence. In this study refolding of GdmCl-denat...

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Autori principali: Yin, Fon-Yi, Chen, Ya-Huei, Yu, Chung-Ming, Pon, Yu-Chin, Lee, Hwei-Jen
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1929020/
https://ncbi.nlm.nih.gov/pubmed/17513375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.104604
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