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Role of acute-phase proteins in interleukin-1-induced nonspecific resistance to bacterial infections in mice.

Treatment with a single low dose (80 to 800 ng) of interleukin-1 (IL-1) 24 h before a lethal bacterial challenge of granulocytopenic and normal mice enhances nonspecific resistance. Since IL-1 induces secretion of acute-phase proteins, liver proteins which possess several detoxifying effects, we inv...

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Autors principals: Vogels, M T, Cantoni, L, Carelli, M, Sironi, M, Ghezzi, P, van der Meer, J W
Format: Artigo
Idioma:Inglês
Publicat: 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC192729/
https://ncbi.nlm.nih.gov/pubmed/7509141
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