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Non-linear dimensionality reduction of signaling networks

BACKGROUND: Systems wide modeling and analysis of signaling networks is essential for understanding complex cellular behaviors, such as the biphasic responses to different combinations of cytokines and growth factors. For example, tumor necrosis factor (TNF) can act as a proapoptotic or prosurvival...

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Bibliographic Details
Main Authors: Ivakhno, Sergii, Armstrong, J Douglas
Format: Artigo
Language:Inglês
Published: BioMed Central 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925119/
https://ncbi.nlm.nih.gov/pubmed/17559646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-1-27
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