Functional characterization of two melanocortin (MC) receptors in lamprey showing orthology to the MC1 and MC4 receptor subtypes

BACKGROUND: The melanocortin (MC) receptors have a key role in regulating body weight and pigmentation. They belong to the rhodopsin family of G protein-coupled receptors (GPCRs). The purpose of this study was to identify ancestral MC receptors in agnathan, river lamprey. RESULTS: We report cloning...

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Bibliografiske detaljer
Main Authors: Haitina, Tatjana, Klovins, Janis, Takahashi, Akiyoshi, Löwgren, Maja, Ringholm, Aneta, Enberg, Johan, Kawauchi, Hiroshi, Larson, Earl T, Fredriksson, Robert, Schiöth, Helgi B
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925065/
https://ncbi.nlm.nih.gov/pubmed/17603878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-7-101
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