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Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism

Many studies have supported a genetic aetiology for autism. Here we report mutations in two X-linked genes, neuroligins NLGN3 and NLGN4, in siblings with autism spectrum disorders. These mutations affect cell adhesion molecules localised at the synapse and suggest that a defect of synaptogenesis may...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jamain, Stéphane, Quach, Hélène, Betancur, Catalina, Råstam, Maria, Colineaux, Catherine, Gillberg, I Carina, Söderström, Henrik, Giros, Bruno, Leboyer, Marion, Gillberg, Christopher, Bourgeron, Thomas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Pub. Co. 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925054/
https://ncbi.nlm.nih.gov/pubmed/12669065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1136
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