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Initiation of Apoptosis and Autophagy by the Bcl-2 Antagonist HA14-1
L1210 murine leukemia cells exposed to an LD(90) concentration of the Bcl-2/Bcl-x(L) antagonist HA14-1 rapidly undergo apoptosis but also develop numerous intracellular vacuoles with double membranes, exhibit enhanced labeling by monodansylcadaverine, and convert the cytosolic protein LC3-I to LC3-I...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1924967/ https://ncbi.nlm.nih.gov/pubmed/17055152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2006.09.009 |
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