Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III

Repair of oxidative damage to DNA bases is essential to prevent mutations and cell death. Endonuclease III is the major DNA glycosylase activity in Escherichia coli that catalyzes the excision of pyrimidines damaged by ring opening or ring saturation, and it also possesses an associated lyase activi...

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Autors principals: Aspinwall, Richard, Rothwell, Dominic G., Roldan-Arjona, Teresa, Anselmino, Catherine, Ward, Christopher J., Cheadle, Jeremy P., Sampson, Julian R., Lindahl, Tomas, Harris, Peter C., Hickson, Ian D.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC19249/
https://ncbi.nlm.nih.gov/pubmed/8990169
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