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Bayesian estimates of linkage disequilibrium
BACKGROUND: The maximum likelihood estimator of D' – a standard measure of linkage disequilibrium – is biased toward disequilibrium, and the bias is particularly evident in small samples and rare haplotypes. RESULTS: This paper proposes a Bayesian estimation of D' to address this problem....
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1924864/ https://ncbi.nlm.nih.gov/pubmed/17592642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-8-36 |
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