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Endostatin gene variation and protein levels in breast cancer susceptibility and severity

BACKGROUND: Endostatin is a potent endogenous anti-angiogenic agent which inhibits tumour growth. A non-synonymous coding polymorphism in the Endostatin gene is thought to affect Endostatin activity. We aimed to determine the role of this Endostatin polymorphism in breast cancer pathogenesis and any...

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Détails bibliographiques
Auteurs principaux: Balasubramanian, Sabapathy P, Cross, Simon S, Globe, Jenny, Cox, Angela, Brown, Nicola J, Reed, Malcolm W
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924861/
https://ncbi.nlm.nih.gov/pubmed/17587451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-107
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