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Histidine Triad-like Motif of the Rotavirus NSP2 Octamer Mediates both RTPase and NTPase Activities

Rotavirus NSP2 is an abundant non-structural RNA-binding protein essential for forming the viral factories that support replication of the double-stranded RNA genome. NSP2 exists as stable doughnut-shaped octamers within the infected cell, representing the tail-to-tail interaction of two tetramers....

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Detalhes bibliográficos
Main Authors: Vasquez-Del Carpio, Rodrigo, Gonzalez-Nilo, Fernando D., Riadi, Gonzalo, Taraporewala, Zenobia F., Patton, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924841/
https://ncbi.nlm.nih.gov/pubmed/16934294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.07.050
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