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Coordination of Hpr1 and Ubiquitin Binding by the UBA Domain of the mRNA Export Factor Mex67

The ubiquitin-associated (UBA) domain of the mRNA nuclear export receptor Mex67 helps in coordinating transcription elongation and nuclear export by interacting both with ubiquitin conjugates and specific targets, such as Hpr1, a component of the THO complex. Here, we analyzed substrate specificity...

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Autors principals: Hobeika, Maria, Brockmann, Christoph, Iglesias, Nahid, Gwizdek, Carole, Neuhaus, David, Stutz, Françoise, Stewart, Murray, Divita, Gilles, Dargemont, Catherine
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924821/
https://ncbi.nlm.nih.gov/pubmed/17475778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-02-0153
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