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Inhibition of Integrin-mediated Crosstalk with Epidermal Growth Factor Receptor/Erk or Src Signaling Pathways in Autophagic Prostate Epithelial Cells Induces Caspase-independent Death

In vivo in the prostate gland, basal epithelial cells adhere to laminin 5 (LM5) via α3β1 and α6β4 integrins. When placed in culture primary prostate basal epithelial cells secrete and adhere to their own LM5-rich matrix. Adhesion to LM5 is required for cell survival that is dependent on integrin-med...

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Detalhes bibliográficos
Main Authors: Edick, Mathew J., Tesfay, Lia, Lamb, Laura E., Knudsen, Beatrice S., Miranti, Cindy K.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924805/
https://ncbi.nlm.nih.gov/pubmed/17475774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-04-0261
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