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Erythropoietin modulation of podocalyxin and a proposed erythroblast niche

Epo's erythropoietic capacity is ascribed largely to its antiapoptotic actions. In part via gene profiling of bone marrow erythroblasts, Epo is now shown to selectively down-modulate the adhesion/migration factors chemokine receptor-4 (Cxcr4) and integrin alpha-4 (Itga4) and to up-modulate grow...

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Detalhes bibliográficos
Main Authors: Sathyanarayana, Pradeep, Menon, Madhu P., Bogacheva, Olga, Bogachev, Oleg, Niss, Knut, Kapelle, William S., Houde, Estelle, Fang, Jing, Wojchowski, Don M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924484/
https://ncbi.nlm.nih.gov/pubmed/17403918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-11-056465
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