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Interplay of impermeability and chromosomal beta-lactamase activity in imipenem-resistant Pseudomonas aeruginosa.

Mutational loss of the D2 porin causes imipenem resistance in Pseudomonas aeruginosa. It was found that this mechanism could function only when the chromosomal beta-lactamase was expressed. Mutants lacking both the beta-lactamase and the D2 porin were almost as susceptible as those that lacked the b...

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Detalles Bibliográficos
Autor principal: Livermore, D M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC192435/
https://ncbi.nlm.nih.gov/pubmed/1329641
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