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Folding of the N-terminal, ligand-binding region of integrin α-subunits into a β-propeller domain

The N-terminal ≈440 aa of integrin α subunits contain seven sequence repeats. These are predicted here to fold into a β-propeller domain. A homologous domain from the enzyme phosphatidylinositol phospholipase D is predicted to have the same fold. The domains contain seven four-stranded β-sheets arra...

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Detalles Bibliográficos
Autor Principal: Springer, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences of the USA 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC19237/
https://ncbi.nlm.nih.gov/pubmed/8990162
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