Folding of the N-terminal, ligand-binding region of integrin α-subunits into a β-propeller domain
The N-terminal ≈440 aa of integrin α subunits contain seven sequence repeats. These are predicted here to fold into a β-propeller domain. A homologous domain from the enzyme phosphatidylinositol phospholipase D is predicted to have the same fold. The domains contain seven four-stranded β-sheets arra...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19237/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8990162/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.1.65 |
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