Attenuated replication of human immunodeficiency virus type 1 with a didanosine-selected reverse transcriptase mutation.
The Leu-74 to Val (Leu74Val) mutation in human immunodeficiency virus type 1 reverse transcriptase (RT) develops as a consequence of didanosine (ddI) therapy and is associated with a decreased susceptibility to ddI. In this report, we provide evidence that the ddI-associated Leu74Val mutation confer...
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| Publié dans: | J Virol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
1997
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192351/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343245/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8846-8851.1997 |
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