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Epstein-Barr virus EBNA3C represses Cp, the major promoter for EBNA expression, but has no effect on the promoter of the cell gene CD21.

EBNA3C is a potent repressor of transcription when bound to DNA as a fusion with the DNA binding domain (DBD) of GALA. A survey of promoters has revealed that the wild-type, unfused EBNA3C can specifically repress expression from reporter plasmids containing the Epstein-Barr virus Cp latency-associa...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Radkov, S A, Bain, M, Farrell, P J, West, M, Rowe, M, Allday, M J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1997
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192319/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343213/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8552-8562.1997
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